FIGURE 1.

Protein networks as targets for bioactive food components. A simplified scheme of how food components reported to induce p53, selected as a prototype interconnecting protein node, may influence proteins that belong to neighboring networks controlling biological processes. Stimulatory effects of p53 are shown in green and repressive effects are shown in red. Proteomic tools are needed to learn about the topology and dynamic behavior of protein networks that impinge on cancer risk and assess quantitative and qualitative influences of food components.