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. Author manuscript; available in PMC: 2012 Jun 13.
Published in final edited form as: J Thorac Oncol. 2008 May;3(5):545–555. doi: 10.1097/JTO.0b013e318170627f

TABLE 1.

ERCC1 Expression-Predicting Response to Chemotherapy

Author N Stage Type of Chemotherapy ERCC1 Level Median Survival p Response CR&PR p
Olaussen et al. 389 I–III Cis-Vinorelbine Low
High		 56 (mo)
50 (mo)		 0.34 NA NA
Lord et al. 56 IIIB–IV Cis-Gemcitabine Low
High		 62 (wk)
20 (wk)		 0.009 52%
36.4%		 0.38
Ceppi et al. 61 III–IV Cis-Gemcitabine Low
High		 17.3 (mo)
10.9 (mo)		 0.0032 NA NA
Rosell et al. 160 IV Cis-Gemcitabine Low
High		 18.3 (mo)
NR		 56.6%
37.7%		 0.02