Table 1. List of proteins identified by LC MS/MS in CD105+ cells that participate in specific canonical pathways as determined by IPA analysis.
Axonal Guidance Signaling | ABLIM3; ADAM29; AKT1; AKT2; CDK5; CRK; EPHB6; GLI2PAK1; GNA12; GNAL; GNAO1; GNAT2; MYL6B; NGEF; NRP1; SRGAP1; PAK2; PRKCA; PRKACB; PRKAR1A; PRKAR2A; PLXNA1; RAC3; RGS3; ROBO1; ROCK1; RRAS2; TUBA1C; TUBA4A |
DNA Methylation and Transcriptional Repression Signaling | CHD3; CHD4; MTA1; RBBP7; MTA2; ARID4B |
Amyloid Processing | AKT1; AKT2; CAPN6; CDK5; CSNK2A2; CSNK2B; PRKACB; PRKAR2A; PRKAR1A |
Molecular Mechanisms of Cancer | AKT1; AKT2; ARHGEF1; CASP6; CDK2; CDK4; CDK6; CRK; DAXX; FOS; GNA12; GNAO1; GNAL; GNAT2; PAK1; PAK2; PRKACB; PRKAR1A; PRKAR2A; PRKCA; RAC3 RAPGEF1; RASGRF2; RHOC; RHOG; RRAS2 |
Proteins detected only in CD105+ cell extracts were analyzed by IPA software to determine their potential role in canonical signalling pathways. Proteins identified to participate in the top four canonical pathways are listed in alphabetical order.