Table 1.

Summary of the incidence of the ERR-γ repeat in patient samples

	Long allele non-carriers	Long allele carriers	Totals	Incidence (%)	Statistics (P value)
					Baseline group
					Healthy: no BC family hx n = 105	Healthy: all n = 174
Healthy volunteers
No BC family hx	100	5	105	4.8	–	0.799
BC family hx	64	5	69	8.2	0.520	0.514
All healthy volunteers	164	10	174	5.7	0.791	–
Cancer patients
Breast cancer	126	21	147	14.3*	0.020	0.013
Other cancers	192	15	207	7.3	0.471	0.791
Total	482	46	528	8.7	–	–

Note: “BC family hx” refers to first degree (sister, daughter, or mother) or second degree (grandmother, aunt, niece, or granddaughter) family members with breast cancer. “Carriers” refer to persons in which the long allele (defined as at least 13 copies of the AAAG motif) is present. Asterisk indicates a statistically significant difference between the incidence of long allele carriers in breast cancer patients, compared to cancer-free volunteers, based on Fisher's exact test (P value = 0.0134, two-tailed comparison). A detailed list of patients and genotyping information is provided as Online Resource 1

BC breast cancer, hx history