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. Author manuscript; available in PMC: 2013 Jun 13.
Published in final edited form as: J Am Chem Soc. 2012 May 23;134(23):9755–9761. doi: 10.1021/ja302692j

Table 1.

MIC values for deoxy-vancomycins 15 and 16 against selected bacterial strains.

Entry Compound MSSAa,b MRSAc VSEd VRE (VanB)e VRE (VanA)f
1 1 0.5 1 2 16 >64
2 15 0.5 1 2 16 >64
3 16 2 4 8 >64 >64
a

MIC values reported in μg/mL.

b

MSSA = methicillin-susceptible S. aureus, ATCC 29213.

c

MRSA = methicillin-resistant S. aureus, ATCC 43300.

d

VSE = vancomycin -susceptible enterococci, ATCC 29212.

e

VRE = vancomycin-resistant enterococci, ATCC 51299.

f

MMX 486. See Supporting Information for additional details.