Table 1.
Entry | Compound | MSSAa,b | MRSAc | VSEd | VRE (VanB)e | VRE (VanA)f |
---|---|---|---|---|---|---|
1 | 1 | 0.5 | 1 | 2 | 16 | >64 |
2 | 15 | 0.5 | 1 | 2 | 16 | >64 |
3 | 16 | 2 | 4 | 8 | >64 | >64 |
MIC values reported in μg/mL.
MSSA = methicillin-susceptible S. aureus, ATCC 29213.
MRSA = methicillin-resistant S. aureus, ATCC 43300.
VSE = vancomycin -susceptible enterococci, ATCC 29212.
VRE = vancomycin-resistant enterococci, ATCC 51299.
MMX 486. See Supporting Information for additional details.