Skip to main content
. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: J Am Geriatr Soc. 2012 May 29;60(6):1070–1077. doi: 10.1111/j.1532-5415.2012.03989.x

Sensitivity Analyses Excluding Codes for…

Full

Definition
Severe Sepsis and

Septic Shock
Cardiovascular Neurologic
New 3-Year Survivors, 1999 (Got Sepsis in 1996)   102,767 102,767 73,051 87,398
New 3-Year Survivors, 2008 (Got Sepsis in 2005)   225,251 207,410 164,540 203,084
% Change, 2008 vs. 1999 219% 202% 225% 232%
New 5-Year Survivors, 2001 (Got Sepsis in 1996)   67,799 67,799 46,966 58,033
New 5-Year Survivors, 2008 (Got Sepsis in 2003)   121,029 119,756 85,743 108,803
% Change, 2008 vs. 2001 179% 177% 183% 187%
Incident Cases 1996 387,330 387,330 289,614 341,586
Incident Cases 2003 656,194 645,379 488,511 594,821
Incident Cases 2005 791,809 689,826 590,572 722,414
Incident Cases 2008 1,015,432 881,334 751,334 853,751
% Change, 2008 vs. 1996 262% 228% 259% 250%
Case Fatality Rates
5-year case fatality rate, incident cases from 1996 82.5% 82.5% 83.8% 83.0%
5-year case fatality rate, incident cases from 2003 81.6% 81.4% 82.5% 81.7%
3-year case fatality rate, incident cases from 1996 73.5% 73.5% 74.8% 74.4%
3-year case fatality rate, incident cases from 2005 71.3% 69.7% 71.9% 71.7%
In-Hospital case fatality rate, incident cases from 1996 28.5% 28.5% 27.6% 30.0%
In-Hospital case fatality rate, incident cases from 2008 15.8% 12.4% 13.0% 16.0%
Contributions to 3-Year Survivorship Change
Population Aging 5.7% 5.7% 5.7% 5.7%
Hospitalizations with Infection per Person 8.6% 8.6% 8.6% 8.6%
Organ dysfunction per Hospitalization with Infection 78.2% 55.2% 77.7% 84.3%
Long-term Survival 8.0% 14.2% 11.3% 10.7%
Contributions to 5-Year Survivorship Change
Population Aging 4.2% 4.2% 4.2% 4.2%
Hospitalizations with Infection per Person 8.6% 8.6% 8.6% 8.6%
Organ dysfunction per Hospitalization with Infection 49.7% 47.3% 49.1% 53.9%
Long-term Survival 5.4% 6.1% 8.2% 7.7%

Sensitivity Analyses Excluding Codes for…

Hematologic Hepatic Renal Respiratory

New 3-Year Survivors, 1999 (Got Sepsis in 1996) 83,898 102,332 82,327 73,260
New 3-Year Survivors, 2008 (Got Sepsis in 2005) 188,885 223,797 124,560 189,416
% Change, 2008 vs. 1999 225% 219% 151% 259%
New 5-Year Survivors, 2001 (Got Sepsis in 1996) 54,794 67470 55,122 48,832
New 5-Year Survivors, 2008 (Got Sepsis in 2003) 98,814 120262 76,004 97,170
% Change, 2008 vs. 2001 180% 178% 138% 199%
Incident Cases 1996 320,965 384,128 284,144 240,175
Incident Cases 2003 544,488 650,126 376,227 467,504
Incident Cases 2005 668,707 783,373 413,788 597,456
Incident Cases 2008 921,573 1,002,340 425,198 824,543
% Change, 2008 vs. 1996 287% 261% 150% 343%
Case Fatality Rates
5-year case fatality rate, incident cases from 1996 82.9% 82.4% 80.6% 79.7%
5-year case fatality rate, incident cases from 2003 81.9% 81.5% 79.8% 79.2%
3-year case fatality rate, incident cases from 1996 73.9% 73.4% 71.0% 69.5%
3-year case fatality rate, incident cases from 2005 71.6% 71.2% 69.7% 68.1%
In-Hospital case fatality rate, incident cases from 1996 29.7% 28.2% 25.8% 20.2%
In-Hospital case fatality rate, incident cases from 2008 16.1% 15.4% 15.7% 10.5%
Contributions to 3-Year Survivorship Change
Population Aging 5.7% 5.7% 5.7% 5.7%
Hospitalizations with Infection per Person 8.6% 8.6% 8.6% 8.6%
Organ dysfunction per Hospitalization with Infection 81.6% 77.8% 26.9% 116.8%
Long-term Survival 8.9% 8.0% 4.7% 4.7%
Contributions to 5-Year Survivorship Change
Population Aging 4.2% 4.2% 4.2% 4.2%
Hospitalizations with Infection per Person 8.6% 8.6% 8.6% 8.6%
Organ dysfunction per Hospitalization with Infection 49.9% 49.6% 17.0% 72.0%
Long-term Survival 6.3% 5.4% 4.1% 2.2%