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. Author manuscript; available in PMC: 2013 Jul 17.
Published in final edited form as: Acc Chem Res. 2012 Feb 21;45(7):1067–1076. doi: 10.1021/ar2002123

Figure 3. Pathways of Endocytosis and Intracellular Trafficking.

Figure 3

Several of the illustrated endocytotic pathways have been associated with the uptake of various types of oligonucleotide conjugates or of ‘free’ oligonucleotides. Various intracellular membranous organelles are also illustrated as are some of the proteins associated with trafficking pathways. The Rab proteins are GTPases that help to guide intracellular traffic. (reproduced with permission23).