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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Arthritis Rheum. 2012 Feb;64(2):579–583. doi: 10.1002/art.33339

Figure 1.

Figure 1

Voxel placement and resulting spectrum on magnetic resonance spectroscopy. A, Axial and sagittal T1-weighted brain images obtained from fibromyalgia patients show single-voxel placements (boxed areas) for the right anterior insula (ant Ins), right posterior insula (post Ins), anterior cingulate (ACC), and occipital cortex (Occ). B, A representative proton magnetic resonance spectroscopy spectrum from the posterior insula is shown, as determined using the multi-echo single-voxel point-resolved spectroscopy technique edited for γ-aminobutyric acid (GABA). The peak for the combined measure of glutamine and glutamate (Glx) is resolved at 3.8 parts per million, and the peak for GABA is resolved at 3.0 ppm, with an inverted N-acetylaspartate (NAA) peak at 2.0 ppm.