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. 2012 Jun 14;18(22):2827–2831. doi: 10.3748/wjg.v18.i22.2827

Table 1.

Logistic regression analysis of genotype frequencies of single nucleotide polymorphisms rs11614913, rs895819 and rs2910164 in colorectal cancer cases and controls in the Czech population

Control
CRC
n % n % OR1 95% Cl Pvalue
A/A 93 43.87 88 44.67 1 0.996a
miR-27a A/G 94 44.34 86 43.65 0.98 (0.64-1.49) 0.950
G/G 25 11.79 23 11.68 1.04 (0.54-1.98) 0.970
AG + GG vs AA 1.01 (0.68-1.51) 0.954
[G] vs [A] 0.999 (0.71-1.39) 0.995
Trend 212 197 0.99 (0.8-1.22) 0.9118a
miR-146a G/G 124 58.49 115 58.38 1 0.761a
C/G 79 37.26 70 35.53 0.93 (0.61-1.41) 0.740
C/C 9 4.25 12 6.09 1.31 (0.52-3.27) 0.556
CG + CC vs GG 1.03 (0.69-1.54) 0.879
[C] vs [G] 1.37 (0.56-3.33) 0.494
Trend 212 197 0.97 (0.79-1.19) 0.7558a
miR-196-a2 C/C 87 41.04 82 41.62 1 0.6098a
C/T 103 48.58 89 45.18 0.95 (0.62-1.45) 0.794
T/T 22 10.38 26 13.2 1.32 (0.69-2.54) 0.415
CT + TT vs CC 1.01 (0.68-1.51) 0.951
[T] vs [C] 1.04 (0.75-1.45) 0.811
Trend 212 197 1.08 (0.8-1.46) 0.5987a

P-values are calculated according to Wald’s test.

a

P-values according to likelihood ratio-test;

1

Age and sex adjusted; CRC: Colorectal cancer; OR: Odds ratio; CI: Confidence interval.