Table 3.
Markers of early left ventricular systolic dysfunction in univariate and multivariate analyses
| OR | 95 % CI | p | |
|---|---|---|---|
| Univariate analysis | |||
| Anterior vs. non-anterior wall STEMI | 30.92 | 11.41–83.75 | <0.0001 |
| Heart failure prior to MI (I or II class according to the NYHA classification) | 7.52 | 3.00–18.83 | <0.0002 |
| Body mass index (for a 10 kg/m2 increase) | 2.76 | 1.22–6.23 | <0.02 |
| Hypertension | 2.11 | 1.13–3.95 | <0.02 |
| Diabetes mellitus | 2.03 | 0.96–4.29 | 0.066 |
| BNP at discharge (for a 100 pg/mL increase) | 1.89 | 1.48–2.43 | <0.0001 |
| TnImax (for a 10 ng/mL increase) | 1.67 | 1.35–2.06 | <0.0001 |
| BNP at admission (for a 100 pg/mL increase) | 1.61 | 1.14–2.28 | <0.01 |
| CRP 24 h after admission (for a 10 mg/L increase) | 1.60 | 1.27–2.00 | <0.0001 |
| CRP at discharge (for a 10 mg/L increase) | 1.55 | 1.24–1.93 | <0.0002 |
| Age (for a 10-year increase) | 1.38 | 0.99–1.94 | 0.056 |
| CRP at admission (for a 10 mg/L increase) | 1.37 | 0.27–7.03 | 0.70 |
| Leukocyte count 24 h after admission (for a 103 per μL increase) | 1.30 | 1.14–1.48 | <0.002 |
| HbA1c (for a 1 % increase) | 1.29 | 1.00–1.66 | <0.05 |
| Admission glycaemia (for a 1 mmol/L increase) | 1.21 | 1.08–1.35 | <0.001 |
| CK-MBmax (for a 10 U/L increase) | 1.08 | 1.04–1.13 | <0.0002 |
| Leukocyte count at admission (for a 103 per μL increase) | 1.06 | 0.96–1.18 | 0.25 |
| Multivariate analysis | |||
| Anterior vs. non-anterior wall STEMI | 26.67 | 9.42–75.52 | <0.001 |
| TnImax (for a 10 ng/mL increase) | 1.39 | 1.10–1.77 | <0.007 |
| CRP at discharge (for a 10 mg/L increase) | 1.38 | 1.01–1.87 | <0.04 |
Univariate analysis shows demographic, clinical, angiographic and biochemical parameters from Tables 1 and 2 with a p value ≤0.1 as well as CRP and leukocyte count independently of a p value
BNP B-type natriuretic peptide, CI confidence interval, CK-MB max maximal activity of isoenzyme MB of creatine kinase, CRP C-reactive protein, MI myocardial infarction, NYHA New York Heart Association, OR odds ratio, STEMI ST-segment-elevation myocardial infarction, TnI max maximal concentration of troponin I