Table 1.
Study type | Number of genes screened | Total number of mutations | Number of genes mutated | Average number of mutations per tumor | Estimated number of driver mutations | Reference(s) |
---|---|---|---|---|---|---|
Exomic | ||||||
Breast (n = 11) | 18,191 | 1243 | 1137 | 84 | 140 | 87, 88 |
Colorectal (n = 11) | 18,191 | 942 | 848 | 76 | 140 | 87, 88 |
Diverse (n = 210) | 518 | 798 | 581 | – | 119 | 94 |
Pancreatic (n = 24) | 20,661 | 1163 | 1007 | 48 | 160 | 98 |
Glioblastoma (n = 21) | 20,661 | 748 | 685 | 47 | 155 | 102 |
Glioblastoma (n = 91) | 601 | 453 | 223 | – | 8 | 103 |
Lung (n = 188) | 623 | 1013 | 348 | – | 26 | 108 |
Genomic | ||||||
Acute myeloid leukemia (n = 1) | – | 500–1000 | 10 | Not applicable | 10 | 82 |