Table 3.
Locus name | Marker | Phenotype | Position (cM)a | Position (Mb) | LOD score | 95% CI | Variance % | p valueb | Significance |
---|---|---|---|---|---|---|---|---|---|
Hmtb4 | D5Mit338 | Clot stability | 59 | 107.7 | 3.1 | 55–66 | 16 | 0.0009 | Significant |
Hmtb5 | D5Mit320 | Bleeding | 70 | 125.5 | 1.5 | 45–75 | 8 | 0.02 | Suggestive |
Hmtb6 | D11Mit336 | Clot stability | 75.0 | 110.5 | 1.7 | 56–75 | 10 | 0.02 | Suggestive |
Hmtb8 | D17Mit20 | Clot stability | 34.3 | 57.0 | 1.7 | 25–52 | 6 | 0.02 | Suggestive |
Hmtb9 | D17Mit39 | Clot stability | 45.3 | 74.0 | 1.2 | 0–56 | 4 | 0.06 | Suggestive |
From Mouse Genome Database (2007). Number of F2 mice analyzed: chromosome 5, n = 79; chromosome 11, n = 76; chromosome 17, n = 130
Chromosome-wide