Table 3.
Gene Ontology (GO) categories enriched/depleted (P < 0.01) of differentially expressed genes after treating HeLa S3 cells with PhenDC3
| GO ID | TERM | P VALUE |
|---|---|---|
| Enriched GO classes | ||
| GO:0044237 | cellular metabolic process | 2.42E-12 |
| GO:0034960 | cellular biopolymer metabolic process | 5.07E-12 |
| GO:0044260 | cellular macromolecule metabolic process | 2.90E-11 |
| GO:0043283 | biopolymer metabolic process | 5.91E-11 |
| GO:0008152 | metabolic process | 1.19E-10 |
| GO:0043170 | macromolecule metabolic process | 2.94E-10 |
| GO:0044238 | primary metabolic process | 8.10E-10 |
| GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 1.91E-07 |
| GO:0010467 | gene expression | 2.15E-07 |
| GO:0009987 | cellular process | 4.16E-07 |
| GO:0043284 | biopolymer biosynthetic process | 1.28E-06 |
| GO:0034961 | cellular biopolymer biosynthetic process | 1.28E-06 |
| GO:0016070 | RNA metabolic process | 1.90E-06 |
| GO:0034645 | cellular macromolecule biosynthetic process | 5.34E-06 |
| GO:0009059 | macromolecule biosynthetic process | 8.73E-06 |
| GO:0046907 | intracellular transport | 0.0001430 |
| GO:0051641 | cellular localization | 0.0002268 |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | 0.0003508 |
| GO:0044249 | cellular biosynthetic process | 0.0007565 |
| GO:0009058 | biosynthetic process | 0.0009248 |
| GO:0051649 | establishment of localization in cell | 0.0013971 |
| GO:0044267 | cellular protein metabolic process | 0.0075149 |
| Depleted GO classes | ||
| GO:0002376 | immune system process | 0.0074009 |
| GO:0007186 | G-protein coupled receptor protein signaling pathway | 0.0063202 |
| GO:0007166 | cell surface receptor linked signal transduction | 0.0002492 |
| GO:0006955 | immune response | 0.0001782 |
| GO:0032501 | multicellular organismal process | 4.93E-06 |