Table 3.
Measure | Sensitivity† | Specificity† | PPV† | NPV† | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | (se) | n | % | (se) | n | % | (se) | n | % | (se) | |
3-month survival | 2974/2984 | 99.7 | (0.1) | 68/2639 | 2.6 | (0.3) | 2974/5545 | 53.6 | (0.7) | 68/78 | 87.2 | (3.8) |
6-month survival | 2329/2360 | 98.7 | (0.2) | 207/3263 | 6.3 | (0.4) | 2329/5385 | 43.3 | (0.7) | 207/238 | 87.0 | (2.2) |
1-year survival | 1762/1823 | 96.7 | (0.4) | 543/3800 | 14.3 | (0.6) | 1762/5019 | 35.1 | (0.7) | 543/604 | 89.9 | (1.2) |
2-year survival | 1235/1329 | 92.9 | (0.7) | 1099/4294 | 25.6 | (0.7) | 1235/4430 | 27.9 | (0.7) | 1099/1193 | 92.1 | (0.8) |
PPV: positive predictive value
NPV: negative predictive value
se: standard error
* As 10% was chosen as the cutoff value for predicted probability, patients with a predicted probability of survival < 10% were classified as a group that would die before the end of observation period, and those with a predicted probability of survival > = 10% were classified as a group that would survive the whole observation period. By comparison of predicted outcomes with actual outcomes, we further calculated the four measures for reflecting the quality of predictions in different perspectives.
† The formulae for these measures are below:
sensitivity = (the number of patients with a predicted probability of survival > = 10%)/(the number of patients who actually survive the whole observation period);
specificity = (the number of patients with a predicted probability of survival < 10%)/(the number of patients who actually died before the end of observation period);
PPV = (the number of patients who actually survive the whole observation period)/(the number of patients with a predicted probability of survival > = 10%);
NPV = (the number of patients who actually died before the end of observation period)/(the number of patients with a predicted probability of survival < 10%).