Table 3.
Effect of SHetA2 on bacterial strains in the Ames test
| Mean ± Standard Deviation Revertants/Plate | Mean ± Standard Deviation Revertants/Plate | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dose (μg)/Plate | TA1535 | TA1537 | TA98 | TA100 | Wpuvr A | Dose (μg)/Plate | TA1535 | TA1537 | TA98 | TA100 | Dose (μg)/Plate | Wpuvr A |
| Without S9 | Without S9 | |||||||||||
| 0 | 15 ± 1 | 8 ± 3 | 33 ± 5 | 129 ± 27 | 23 ± 3 | 0 | 18 ± 1 | 13 ± 2 | 19 ± 6 | 134 ± 13 | 0 | 20 ± 1 |
| 0.31 | 20 ± 5 | 5 ± 0 | 41 ± 3 | 136 ± 14 | 20 ± 2 | 0.31 | 14 ± 3 | 10 ± 3 | 23 ± 4 | 125 ± 12 | 2.44 | 18 ± 4 |
| 0.61 | 15 ± 3 | 10 ± 2 | 33 ± 7 | 140 ± 6 | 28 ± 2 | 0.61 | 16 ± 5 | 10 ± 2 | 29 ± 6 | 141 ± 8 | 4.88 | 16 ± 5 |
| 1.22 | 10 ± 2 | 8 ± 2 | 37 ± 4 | 157 ± 13 | 21 ± 4 | 1.22 | 19 ± 6 | 13 ± 1 | 25 ± 2 | 150 ± 12 | 9.77 | 17 ± 3 |
| 2.44 | 10 ± 4 | 5 ± 1 | 34 ± 3 | 130 ± 6 | 23 ± 4 | 2.44 | 20 ± 2 | 13 ± 2 | 27 ± 2 | 148 ± 8 | 19.53 | 19 ± 3 |
| 4.88 | CT | 3 ± 2 | 22 ± 6 | 72 ± 17 | 27 ± 3 | 4.88 | 5 ± 2 | 2 ± 1 | 7 ± 2 | 56 ± 13 | 39.06 | 21 ± 2 |
| 9.77 | CT | 1 ± 1 | 5 ± 3 | 25 ± 29 | 20 ± 1 | 9.77 | CT | CT | CT | CT | 78.13 | 12 ± 2 |
| 19.53 | CT | CT | CT | 14 ± 1 | 19 ± 6 | 156.3 | 9 ± 3 | |||||
| With S9 (5%) | With S9 (10%) | |||||||||||
| 0 | 14 ± 1 | 7 ± 2 | 48 ± 7 | 145 ± 23 | 28 ± 2 | 0 | 15 ± 1 | 9 ± 2 | 34 ± 1 | 132 ± 24 | 0 | 20 ± 3 |
| 0.31 | 13 ± 3 | 11 ± 2 | 37 ± 2 | 144 ± 4 | 26 ± 6 | 1.22 | 15 ± 3 | 4 ± 1 | 35 ± 2 | 133 ± 10 | 2.44 | 16 ± 2 |
| 0.61 | 17 ± 1 | 13 ± 2 | 38 ± 5 | 134 ± 18 | 26 ± 6 | 2.44 | 14 ± 4 | 12 ± 1 | 39 ± 5 | 144 ± 3 | 4.88 | 19 ± 2 |
| 1.22 | 16 ± 2 | 12 ± 3 | 48 ± 8 | 148 ± 20 | 21 ± 2 | 4.88 | 14 ± 4 | 12 ± 1 | 41 ± 6 | 156 ± 3 | 9.77 | 23 ± 3 |
| 2.44 | 13 ± 2 | 8 ± 3 | 43 ± 3 | 150 ± 9 | 30 ± 2 | 9.77 | 13 ± 6 | 12 ± 4 | 40 ± 2 | 135 ± 14 | 19.53 | 22 ± 3 |
| 4.88 | 9 ± 4 | 11 ± 1 | 45 ± 10 | 154 ± 14 | 30 ± 2 | 19.53 | 11 ± 0 | 11 ± 4 | 39 ± 6 | 166 ± 21 | 39.06 | 20 ± 1 |
| 9.77 | 9 ± 3 | 12 ± 4 | 51 ± 8 | 157 ± 4 | 23 ± 6 | 39.06 | 5 ± 2 | CT | 44 ± 8 | 162 ± 22 | 78.13 | 19 ± 3 |
| 19.53 | 5 ± 1 | 5 ± 3 | 53 ± 11 | 166 ± 8 | 27 ± 4 | 78.13 | CT | CT | 35 ± 2 | 26 ± 2 | 156.3 | 9 ± 1 |
| Experiment 1 | Experiment 2 | |||||||||||
CT = Cytoxic.