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. Author manuscript; available in PMC: 2012 Jun 14.
Published in final edited form as: Epilepsia. 2011 Dec 9;53(1):157–167. doi: 10.1111/j.1528-1167.2011.03345.x

Figure 4.

Figure 4

Real-time measures of extracellular glutamate can be recorded using MEAs. (A) Typical traces measuring resting glutamate levels in kindled ( Inline graphic) and control ( Inline graphic) animals. (B) Spontaneous transient glutamate peaks in DG of kindled ( Inline graphic) and control ( Inline graphic) rats with amplitude and time indicated. Concentration of glutamate is calculated by multiplying the recorded current by the slope obtained during calibration of the electrode. Calibrations are performed as described previously (Burmeister & Gerhardt, 2001).

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