Table 2.

Mean arterial pressure, heart rate, plasma creatinine and alanine aminotransferase concentrations (ALAT) throughout the experimental protocol in the different groups.

	n	Baseline	Cardiopulmonary resuscitation					Day 1 (n)
			15min	60min	180min	360min	480min
			Epinephrine perfusion		No	Yes	Yes		Yes	Yes	No
Heart rate (beat/min)
Control 5′	10	257±11	222±8	221±7	243±11	216±7	220±9	234±8 (10)
H-TLV 5′	10	259±10	202±12	174±6 *	177±9 *	245±9	234±8	244±10 (10)
Control 10′	10	263±10	219±6	220±10	198±8	221±11	231±13	256±17 (7)
H-TLV 10′	10	267±8	167±10 *	158±8 *	167±11	208±12	240±11	252±7 (8)
Saline 10′	7	266±7	200±10	153±7 *	155±13 *	219±10	218±10	226±16 (6)
N-TLV 10′	7	256±13	216±19	207±9	213±12	207±9	221±15	240±28 (2)
Mean arterial pressure (mmHg)
Control 5′	10	81±3	83±4	82±3	83±1	83±4	80±4	83±4 (10)
H-TLV 5′	10	80±7	81±3	82±5	82±3	83±3	79±3	82±4 (10)
Control 10′	10	80±5	82±3	83±3	81±4	83±2	80±3	79±4 (7)
H-TLV 10′	10	83±4	81±4	82±3	81±3	81±4	80±4	79±6 (8)
Saline 10′	7	80±8	86±6	89±2	78±5	82±5	76±6	83±9 (6)
N-TLV 10′	7	78±7	78±5	78±1	78±4	78±5	75±7	88±4 (2)
Plasma creatinine concentrations (mg/l)
Control 5′	10	10±1	11±1	-	10±1	-	-	10±1 (10)
H-TLV 5′	10	10±0	12±1	-	11±1	-	-	10±1 (10)
Control 10′	10	9±1	13±1	-	14±2	-	-	11±1 (7)
H-TLV 10′	10	10±0	13±1	-	12±1	-	-	11±1 (8)
Saline 10′	7	9±1	10±1	-	10±1	-	-	10±1 (6)
N-TLV 10′	7	9±1	11±1	-	12±1	-	-	13±6 (2)
Plasma ALAT concentrations (UI/l)
Control 5′	10	29±5	31±4	-	33±4	-	-	35±9 (10)
H-TLV 5′	10	25±3	26±2	-	43±5	-	-	30±6 (10)
Control 10′	10	44±13	79±25	-	115±32	-	-	60±17 (7)
H-TLV 10′	10	48±3	65±5	-	111±27	-	-	83±14 (8)
Saline 10′	7	32±2	48±4	-	101±30	-	-	62±27 (6)
N-TLV 10′	7	31±5	66±10	-	96±13	-	-	94±37 (2)

^*p<0.05 vs corresponding control value; TLV, total liquid ventilation; H-TLV, hypothermic TLV; N-TLV, normothermic TLV; Saline, hypothermia induced by intravenous administration of cold saline combined to external cooling.