Table 1.
Pulmonary hemodynamic, physiological, and biological variables in 124 patients with COPD and correlations with telomere length in circulating leukocytes.
| Mean±SEM | Correlation with telomere length | ||
|---|---|---|---|
| r | P value | ||
| Females/males | 29/95 | - | - |
| Telomere length (T/S ratio) | 0.56±0.01 | - | - |
| Age, y | 64.1±0.7 | − 0.20 | 0.02 |
| Pack-years | 50.7±2.4 | 0.05 | 0.52 |
| FEV1, % | 41.5±1.6 | 0.04 | 0.65 |
| FEV1, L | 1.1±0.0 | 0.09 | 0.29 |
| FVC, L | 2.7±0.1 | 0.06 | 0.45 |
| FEV1/FVC, % | 47.4±1.2 | 0.02 | 0.82 |
| Pap, mmHg | 24.6±0.6 | − 0.20 | 0.04 |
| Pcwp, mmHg | 10.4±0.4 | 0.04 | 0.64 |
| Rap, mmHg | 5.7±0.3 | 0.02 | 0.82 |
| Cardiac index, L/min/m2 | 2.7±0.1 | 0.02 | 0.82 |
| PVR, Wood Units | 3,1±0.1 | − 0.29 | 0.01 |
| IL-6, pg/mL | 3.8±0.4 | − 0.20 | 0.04 |
| IL-8, pg/mL | 13.4±0.9 | 0.05 | 0.59 |
| IL-1β, pg/mL | 0.81±0.1 | 0.02 | 0.85 |
| TGF-β, pg/mL | 28,4±1,4 | 0.03 | 0.77 |
| TNF-α, pg/mL | 1.7±0.1 | − 0.03 | 0.73 |
| MCP-1, pg/mL | 530.7±23.0 | − 0.18 | 0.06 |