Skip to main content
. Author manuscript; available in PMC: 2012 Jun 15.
Published in final edited form as: Circ Res. 2011 Jun 30;109(5):543–553. doi: 10.1161/CIRCRESAHA.111.241299

Table 2.

Comparison of clinical characteristics and pathological variables between patients with COPD and control smokers

Patients (n = 14) Controls (n = 13) P value
Females/males 3/11 4/9
Age, y 64.2 ± 1.8 59.1 ± 3.3 0.15
Pack-years 49.4 ± 6.1 37.1 ± 4.0 0.10
FEV1, % 74.7 ± 4.1 91.9 ± 5.5 0.003
FEV1, L 2.05 ± 0.15 2.69 ± 0.25 0.027
FVC, L 3.2 ± 0.2 3.8 ± 0.4 0.21
FEV1/FVC 63.6 ± 1.7 77.0 ± 1.4 0.0001
Systolic Pap, mmHg 33.2 ± 2.9 25.0 ± 1.6 0.04
Wall thickness area, Ø 0–99 μm, 10−4 mm2 41.0 ± 3.3 27.4 ± 1.7 0.001
Wall thickness area, Ø 100–199 μm, 10−4 mm2 123.2 ± 5.2 87.9 ± 5.4 0.00001
Wall thickness area, Ø 200–399 μm, 10−4 mm2 292.0 ± 13.0 242.9±23.2 0.05
Wall thickness area, % 72.0 ± 1.9 55.8 ± 1.9 0.0001

Data are means±SEM. P values are for the comparisons between patients and smokers.