Table 2.
Patients (n = 14) | Controls (n = 13) | P value | |
---|---|---|---|
Females/males | 3/11 | 4/9 | |
Age, y | 64.2 ± 1.8 | 59.1 ± 3.3 | 0.15 |
Pack-years | 49.4 ± 6.1 | 37.1 ± 4.0 | 0.10 |
FEV1, % | 74.7 ± 4.1 | 91.9 ± 5.5 | 0.003 |
FEV1, L | 2.05 ± 0.15 | 2.69 ± 0.25 | 0.027 |
FVC, L | 3.2 ± 0.2 | 3.8 ± 0.4 | 0.21 |
FEV1/FVC | 63.6 ± 1.7 | 77.0 ± 1.4 | 0.0001 |
Systolic Pap, mmHg | 33.2 ± 2.9 | 25.0 ± 1.6 | 0.04 |
Wall thickness area, Ø 0–99 μm, 10−4 mm2 | 41.0 ± 3.3 | 27.4 ± 1.7 | 0.001 |
Wall thickness area, Ø 100–199 μm, 10−4 mm2 | 123.2 ± 5.2 | 87.9 ± 5.4 | 0.00001 |
Wall thickness area, Ø 200–399 μm, 10−4 mm2 | 292.0 ± 13.0 | 242.9±23.2 | 0.05 |
Wall thickness area, % | 72.0 ± 1.9 | 55.8 ± 1.9 | 0.0001 |
Data are means±SEM. P values are for the comparisons between patients and smokers.