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. 2012 Jun 14;7(6):e38326. doi: 10.1371/journal.pone.0038326

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Fang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Screening assay of DUB mutant strains in the larvae model revealed various degrees of virulence. B. Reconstituted strain (ubp5Δ+UBP5) completely restored the virulence in G. mellonella killing assay. C. Deletion of Ubp5 exhibited significantly attenuated virulence in murine inhalation infection model.