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. 2012 Jun 14;8(6):e1002763. doi: 10.1371/journal.ppat.1002763

Figure 1. Role of STAT1 in the hematopoietic compartment.

Figure 1

C57BL/6N (WT) and Stat1−/− mice were lethally irradiated and bone marrow of the respective donor mice was transferred into recipient mice. After engraftment mice were infected i.p. with 1×10∧5 Lm and the bacterial load of spleen (1A) and liver (1B) was determined and medians were calculated (n = 5). Statistical significance was determined using the Mann-Whitney Test. Serum of infected mice (n = 5) was collected and cytokines (IL6, IL12p70, IL22, IL10, IFNγ, TNFα, MCP1, IP10, Rantes, MCP3) were determined (1C). Means and standard deviations are shown.