Figure 7. Adaptive immunity to Listeria monocytogenes in mice with tissue-restricted Stat1 ablation.

Immunised and naïve mice were infected i.v. with 1×10∧5 Lm and bacterial load was determined 48 h after infection (n = 4–5) (7A) or survival of 7 mice of each genotype was monitored (7B). Serum of immunised and naïve mice was analysed for the presence of IFNγ (7C). One representative result of at least two independently performed experiments is shown (n = 4–5).