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. 2012 Jun 14;8(6):e1002760. doi: 10.1371/journal.ppat.1002760

Table 1. YfiR-insensitive YfiN alleles.

Location in YfiN Residue change Notes
First TM helix A33T
V40A
PAS, dimerization interface P51S
R58C
S59P Equivalent mutation activates AwsX [35].
Y62H
A66V
A67P
A67V
V68A
F70L
E87K Mutation present in Clin110.
Second TM helix G162S
A171V
G173S
G173D Mutation present in SCV20265.
HAMP D204N Mutation at the equivalent position activates Tsr [59].
A226T
L228F
E232D Mutation at the equivalent position activates NarX [58].

PAS refers to the periplasmic PAS domain; HAMP refers to the HAMP domain.