. Author manuscript; available in PMC: 2012 Aug 1.

Published in final edited form as: J Pharm Sci. 2011 Mar 15;100(8):3345–3356. doi: 10.1002/jps.22529

Table 6.

Particle Mean Diameter, PMD (nm), Polydispersity index (PDI), and Zeta Potential (ζ, mV) of the SLNs using the Optimal Point Obtained from the BBD

Run	PMD/PDI after 1st Layer (PAA)	PMD/PDI after 2nd Layer (PLL)	PMD/PDI after 3rd Layer (Heparin)	ζ after 1st Layer (PAA)	ζ after 2nd Layer (PLL)	ζ after 3rd Layer (Heparin)
1	371/0.334	159/0.441	165/0.473	6.81	55.53	− 55.96
2	361/0.317	346/0.269	165/0.283	9.20	51.16	− 55.06
3	402/0.421	143/0.338	131/0.285	9.00	43.50	− 42.20
Average values ± SEM	378 ± 12.34/0.357 ± 0.032	216 ± 65.16/0.349 ± 0.049	153.66 ± 11.33/0.347 ± 0.063	8.34 ± 0.77	50.06 ± 3.52	− 51.07 ± 4.44