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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: J Med Chem. 2012 May 21;55(11):5413–5424. doi: 10.1021/jm300378k

Figure 2. Screening of Reversal Abilities against KB (A) and KBvin (B).

Figure 2

Note: a Concentration of compounds: 10 μM, b Survival rate (%) was measured by SRB method using KB and KBvin cells in the presence (+) or absence (−) of paclitaxel (TAX). Compounds with survival rates below 20 % were considered very potent and moved to further experiments. cGroup (I) saturated acyclic alkyl; (II) cyclic alkyl ; (III) unsaturated; (IV) polar; (V): aromatic; (VI): halogenated.