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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: J Med Chem. 2012 May 21;55(11):5413–5424. doi: 10.1021/jm300378k

Figure 4. Dose response effect of compounds 6 and 23 on sensitization of KBvin to TAX.

Figure 4

Multidrug resistant KBvin cells were treated with various concentrations of compounds 6 or 23 in the presence of 100 nM TAX, an absolutely non-toxic concentration for KBvin. Data are expressed as mean ± SE of three independent experiments. Calculated median effective concentration (EC50) of compounds 6, 23, or VRP was 2.81 μM, 1.87 μM or 2.71 μM, respectively.