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. Author manuscript; available in PMC: 2013 Jun 14.
Published in final edited form as: J Med Chem. 2012 May 21;55(11):5413–5424. doi: 10.1021/jm300378k

Figure 5. Effect of compounds on P-gp function in KBvin cells.

Figure 5

KBvin cells were pre-treated with compounds followed by addition of calcein-AM. The cellular accumulation of calcein is represented by the relative fluorescent unit (×104 RFU). Cellular accumulation of calcein demonstrates inhibition of efflux activity of P-gp. Data with mean ± SD of three independent experiments are shown in suppl. Table S2.