Table 1.

Reversal Effects with Paclitaxel (TAX), Vincristin (VCR), and Doxorubicin (DOX) in KBvin

Group	Cmpda	IC50 of TAX (nM)b	Foldc	IC50 of VCR (nM)	Fold	IC50 of DOX (nM)	Fold
	TAX	976.8	-	2520.7	-	1942.3	-
I	4	82.93	12	80.96	31	507.5	4
	5	46.52	21	41.42	61	284.0	7
	6	26.15	37	7.22	349	42.6	46
	7	30.50	32	50.81	50	510.9	4
	8	37.06	26	35.92	70	93.9	21
	9	8.72	112	31.75	79	339.7	6
	10	40.74	24	15.65	161	221.5	9
	11	39.11	25	47.31	53	61.9	31
II	13	48.65	20	8.14	310	86.3	23
	14	39.89	24	10.55	239	65.8	30
III	15	9.55	102	10.98	230	547.8	4
	16	2.99	326	4.50	560	291.5	7
	17	47.45	21	46.53	54	573.9	3
V	19	7.65	167	20.21	101	157.7	9
	20	46.82	27	39.61	51	130.8	11
	21	47.23	27	40.53	50	131.4	11
	22	14.25	89	10.10	202	68.80	21
	23	4.41	222	4.45	566	84.2	23
	VRP	31.87	31	23.04	109	219	9

^aConcentration of compound: 10 μM,

^bSD was shown in Supporting Information,

^cThe reversal fold values were calculated as: Reversal fold = IC₅₀ (anticancer drug alone) / IC₅₀ (anticancer drug + test compound).