Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of ortho-substituted biphenyl mannosides
a. Reagents and conditions: (a) BF3-Et2O, CH2Cl2, reflux; (b) 3-substituted phenyl boronic acid derivatives, Cat. Pd(PPh3)4, Cs2CO3, dioxane/water(5/1), 80 °C; (c) Cat. MeONa, MeOH, rt; (d) MeNH2/EtOH, rt; (e) bis(pinacolato)diboron, Cat. Pd(dppf)Cl2, KOAc, DMSO, 80 °C.
