FIGURE 1.

Chemical structures of different HS constructs. A, the general structure of all 10 different constructs. The top left structure shows the structures of those constructs without iduronic acid residues. The top right structure shows the structures of those constructs with iduronic acid residues. Each individual polysaccharide construct is shown in the table underneath those two generic structures. B, the structure of a decasaccharide (10-mer, 15b) that displays full binding ability to the Stabilin receptors as described under “Results.” To maintain clarity, the structures of other oligosaccharide constructs are not shown. The abbreviated structures are listed in Table 1.