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. 2012 Apr 18;287(25):21121–21129. doi: 10.1074/jbc.M112.341016

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 7. — Model of Alp12 filament. The interactions between monomers in the Alp12 protofilament are grossly similar to those in the actin protofilament. The red monomers have been aligned, and the subdomains labeled are the barbed (+) and pointed (−) ends of actin. The Alp12 strand is composed of two parallel protofilaments in an arrangement that is not similar to actin. The Alp12 filament is composed of two antiparallel strands connected through subdomain 3, possibly through a β-sheet interaction (inset).