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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Nat Rev Nephrol. 2011 Nov 1;8(1):43–51. doi: 10.1038/nrneph.2011.168

Figure 5.

Figure 5

Immunofluorescence and electron microscopy evaluation of tubulointerstitial damage associated with circulating monoclonal free light chains. a | and b | show examples of immunofluorescence for κ light chains. Linear staining along the tubular basement membranes represents κ light chains (negative for λ light chains). c | Electron microscopy findings of prominent tubular damage and interstitial inflammatory infiltrate. Focal punctate electron-dense material around tubular basement membranes represents deposits of free light chains.