. Author manuscript; available in PMC: 2013 Apr 1.

Published in final edited form as: Pregnancy Hypertens. 2012 Apr 1;2(2):158–163. doi: 10.1016/j.preghy.2012.01.005

Table 2.

Relationship between sFlt1, sEng and preeclampsia within the second trimester

	*Preeclampsia*			*No PE*			^α*p-value*
	Mean (SD)	N	Median	Mean (SD)	N	Median
sFlt1 (pg/mL)	1256.0 (682.4)	211	1122.7	1173.1 (592.2)	213	1068.2	0.10
sEng (ng/mL)	4.3 (1.1)	211	4.2	4.1 (1.1)	213	3.9	0.09

	*Severe Preeclampsia*			*No PE*			^α*p-value*
	Mean (SD)	N	Median	Mean (SD)	N	Median
sFlt1 (pg/mL)	1332.7 (769.5)	59	1186.4	1173.1 (592.2)	213	1068.2	0.04
sEng (ng/mL)	4.4 (1.2)	59	4.2	4.1 (1.1)	213	3.9	0.05

	*Preterm (<37 weeks) Preeclampsia*			*No PE*			^α*p-value*
	Mean (SD)	N	Median	Mean (SD)	N	Median
sFlt1 (pg/mL)	1195.2 (772.9)	45	993.0	1173.1 (592.2)	213	1068.2	0.97
sEng (ng/mL)	4.4 (1.2)	45	4.2	4.1 (1.1)	213	3.9	0.16

	*Early Preterm (<34 weeks)* *Preeclampsia*			*No PE*			^α*p-value*
	Mean (SD)	N	Median	Mean (SD)	N	Median
sFlt1 (pg/mL)	915.6 (402.6)	8	884.5	1173.1 (592.2)	213	1068.2	0.22
sEng (ng/mL)	4.0 (0.8)	8	4.3	4.1 (1.1)	213	3.9	0.99

	*Preeclampsia with SGA<5^th* *percentile*			*No PE*			^α*p-value*
	Mean (SD)	N	Median	Mean (SD)	N	Median
sFlt1 (pg/mL)	1311.2 (500.6)	17	1347.8	1173.1 (592.2)	213	1068.2	0.21
sEng (ng/mL)	4.8 (0.8)	17	4.5	4.1 (1.1)	213	3.9	p<.0001

^α

based on log transformed sFlt1 and sEng, base 2