Table 1.
Characteristics | N | % or mean ± SD |
---|---|---|
Mother and Family | ||
Maternal age at enrollment, y | 1210 | 32.5 ± 5.0 |
Race/Ethnicity | ||
White | 892 | 73.8% |
Black or African American | 139 | 11.5% |
Hispanic or Latina | 67 | 5.5% |
Other | 111 | 9.2% |
Parity | ||
Nulliparous | 577 | 47.7% |
1 | 434 | 35.9% |
2 | 153 | 12.6% |
≥3 | 46 | 3.8% |
Pre-pregnancy body mass index (kg/m2) | 1206 | 24.6 ± 5.1 |
Smoking during index pregnancy | ||
No | 1062 | 89.7% |
Yes | 122 | 10.3% |
Mother’s PPVT-III scorea | 1181 | 106.1 ± 14.5 |
Highest grade level completed by mother | ||
Some college or less | 340 | 28.1% |
College graduate or more | 869 | 71.9% |
Highest grade level completed by father | ||
Some college or less | 345 | 30.7% |
College graduate or more | 778 | 69.3% |
Maternal dietary intakeb | ||
Folate, periconceptional supplementsc (µg/d) | 1148 | 405 ± 405 |
Vitamin B12, periconceptional supplements (µg/d) | 1148 | 4.5 ± 14.0 |
First Trimester | ||
Total energy intake (kcal/d) | 1148 | 2090 ± 655 |
Folate, total (µg/d) | 1148 | 949 ± 390 |
Folate, food sources (µg/d) | 1148 | 367 ± 126 |
Vitamin B12, total (µg/d) | 1148 | 10.8 ± 15.7 |
Vitamin B12, food sources (µg/d) | 1148 | 6.3 ± 4.0 |
Choline (mg/d) | 1148 | 332 ± 63 |
Betaine (mg/d) | 1148 | 243 ± 108 |
Methionine (mg/d) | 1148 | 2053 ± 408 |
Iron (mg/d) | 1148 | 34.2 ± 17.6 |
Fish (servings/wk) | 1148 | 1.7 ± 1.4 |
Second Trimester | ||
Total energy intake (kcal/d) | 1083 | 2139 ± 607 |
Folate, total (µg/d) | 1083 | 1272 ± 381 |
Folate, food sources (µg/d) | 1083 | 367 ± 128 |
Vitamin B12, total (µg/d) | 1083 | 10.6 ± 6.4 |
Vitamin B12, food sources (µg/d) | 1083 | 6.3 ± 3.6 |
Choline (mg/d) | 1083 | 325 ± 64 |
Betaine (mg/d) | 1083 | 234 ± 103 |
Methionine (mg/d) | 1083 | 2065 ± 375 |
Iron (mg/d) | 1083 | 49.4 ± 24.2 |
Fish (servings/wk) | 1083 | 1.6 ± 1.4 |
Child | ||
Sex, % female (n) | 608 | 50.3% |
Age at 3 y testing (mo) | 1210 | 39.5 ± 4.1 |
Speaks English as a second language, % (n) | 41 | 3.4% |
Cognitive tests scores at age 3 y | ||
PPVT-III | 1186 | 103.9 ± 14.3 |
WRAVMA | ||
Total standard | 1147 | 102.3 ± 11.2 |
Drawing | 1195 | 99.4 ± 11.2 |
Matching | 1167 | 108.0 ± 13.6 |
Pegboard | 1192 | 98.4 ± 10.7 |
PPVT, Peabody Picture Vocabulary Test
Nutrient values are adjusted for total-energy intake (residuals method)
Intake from supplements at 0–4 wk of gestation