Table 3.
Multivariable Logistic Regression Assessment of Viral and Host Factors Associated with IFG and IGT
| IFG | ||
|---|---|---|
| Characteristic | Unadjusted Odds Ratio (95% CI) | *Adjusted Odds Ratio (95% CI) |
| Non-Caucasian Race** (vs. Caucasians) | 23.1 (2.8–187.0) | 24.7 (3.0–206.3) |
| Inflammation on Liver Biopsy (Grade ≥ 2 vs. < 2) | 7.9 (1.2–53.4) | 11.0 (1.4–87.0) |
| BMI (per 5 units), kg/m2 | 3.4 (1.2–9.8) | 3.1 (1.07–8.9) |
| IGT (Isolated IGT or IFG/IGT) | ||
| Characteristic | Unadjusted Odds Ratio (95% CI) | †Adjusted Odds Ratio (95% CI) |
| SSPG (per 10 units), mg/dL | 1.1 (1.02–1.2) | 1.1 (1.01–1.2) |
| Non-Caucasian Race** (vs. Caucasians) | 14.8 (1.7–127.3) | 19.7 (1.7–224.3) |
*
Adjusted for age, sex, and HCV genotype.
†
Adjusted for age, sex, BMI, and HCV genotype.
**
Each of the non-Caucasian racial categories had a positive association with pre-diabetes and these races were combined due to small sample size to improve the precision of the point estimates.
BMI, body mass index; HCV, hepatitis C virus; SSPG, steady-state plasma glucose.