Table IV.
Percentage of Hypertensive Children Who Used a Prescription Drug by Age and Drug Class, 2008
| Therapeutic Category Drug Class | Percentage | P Value | |||||
|---|---|---|---|---|---|---|---|
| Total, % | 0 to <6 y, % | 6 to <12 y, % | 12 to <18 y, % | 0 to <6 vs 6 to <12 | 0 to <6 vs 12 to <18 | 6 to <12 vs 12 to <18 | |
| All drugs | 37.4 | 44.3 | 30.9 | 38.1 | .001 | .01 | |
| Cardiovascular agents | 34.1 | 36.5 | 28.9 | 35.0 | .03 | ||
| Angiotensin‐converting enzyme inhibitors | 17.6 | 19.6 | 15.6 | 17.8 | |||
| Angiotensin II receptor antagonists | 2.6 | 0.9 | 1.6 | 3.0 | |||
| Antihypertensive combinationa | 2.8 | 0.9 | 0.6 | 3.6 | .001 | ||
| β‐Adrenergic antagonists without ISAb | 6.7 | 3.0 | 5.1 | 7.4 | .04 | ||
| Calcium channel antagonists | 9.0 | 15.2 | 8.2 | 8.6 | .012 | .003 | |
| Centrally acting antiadrenergic agents | 3.8 | 3.5 | 4.9 | 3.6 | |||
| Electrolyte‐caloric‐water balance agents | 6.5 | 11.3 | 6.6 | 6.0 | .005 | ||
| Loop diuretics | 1.7 | 7.8 | 2.3 | 0.9 | .001 | <.0001 | .04 |
| Thiazides and related agents | 3.7 | 3.0 | 3.5 | 3.8 | |||
Abbreviation: ISA, intrinsic sympathomimetic activity. Drug classes included in this Table met the minimum threshold of a 1.0% user rate. P values are based on pair‐wise chi‐square test adjusting for multiplicity, unless otherwise indicated. aBased on Fisher exact test adjusting for multiplicity.