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BFA sensitivity of ABCB4 requires other ARF-GEFs besides GNOM, but endocytosis is independent from GNL1. A and B, Fluorescence images of ABCB4-GFP in the BFA-resistant GNOM background (GNOMM696L) after treatments without BFA (A) or with BFA (50 μm, 1 h; B). C and D, Fluorescence images of ABCB4-GFP after treatment with BFA (25 μm, 1 h) in GNL1(C) or in gnl1 (D). Bars + 10 μm. [See online article for color version of this figure.]
