Table 1.

Phenotypes of mice deficient in TNF, LTs, or their receptors

	Splenic marginal zone	Primary lymphoid follicles	Secondary lymphoid follicles (germinal centers)	FDC networks	Lymphnode	PP	Thymus	Organ infiltrates
TNF = TNFα	Enlarged	Absent	Absent	Absent	Normal	Present	Normal	Absent
p55 TNFR		Absent	Absent	Absent	Normal	Present	Normal	Absent
p75 TNFR		Normal	Normal	Normal	Normal	Normal	Normal	Normal
LTα = TNFβ	Disturbed	Absent	Absent	Absent	Absent	Absent	Normal
LTβ	Disturbed	Absent	Absent	Absent	Partially absent*	Absent	Normal	Massive†

*Cervical and mesenterical lymphnodes present. 

^†CD4⁺ cells and B cells.