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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Transl Res. 2011 Nov 8;160(1):84–94. doi: 10.1016/j.trsl.2011.10.003

Table 2.

Cytokine/chemokine profile analyses at 23 weeks found high levels of TNFα and several other inflammatory mediators in TNFR1/R2-/- mice with arthritis contributing to the chronic inflammatory hypersensitivity. Relative levels in serum of TNFR1/R2-/- mice were compared to wild type mice and expressed as relative dot blot intensity (arbitrary units, a.u.).

TNFR1/R2-/-
(a.u.)
WT
(a.u.)
Fold Increases TNFR1/R2-/- vs. Controls
TNFα 5911.39±851.78 705.94±49.6 8.37 *
 CCL5 (RANTES) 4192.16±1000.73 1780.85±158.94 2.35 *
 CCL2 (MCP-1) 4263±289.09 2091.52±310.0 2.04 *
 CXCL10 (IP-10) 4922.79±652.51 2394.71±628.45 2.06 *
 CXCL1 5587.85±628.34 3526.53±190.43 1.58 *
 CXCL9 (MIG) 4840.78±1594.37 1946.71±1946.71 2.49
*

indicates p≤0.05.