Fig. 2.

Pedigree of a second family, with sensorineural hearing loss, that has been mapped to an interval which overlaps with the DFNA4 locus. Black and yellow chromosomes are inherited from the affected father, solid blue and white from the unaffected mother, hatched green and hatched blue contributed by unaffected spouse in the second generation. Obligate crossovers in individuals 10 and 11 define the flanking markers. (squares, male; circles, female; black filling indicates affected individual, and black chromosome co-segregates with defect). Numbers beside each chromosome indicate alleles for each marker.