TABLE I.
Characteristics of Actin-Binding Proteins Identified by F-Actin-Affinity Chromatography from ADP-Activated Human Platelets
| Category | Cell type | Staining pattern | Ab no. | Molecular-weight (kDa) |
|---|---|---|---|---|
| 1 | Platelets Fibroblasts Muscle |
Contractile ring Perinuclear Nonreactive |
6 18 |
65 65 |
| 2 | Platelets Fibroblasts Muscle |
Leading edge Leading edge and perinuclear Z-band in muscle |
7 | 95 |
| 3 | Platelets Fibroblasts Muscle |
Contractile ring Stress fibers Both Z and A bands |
14 16 |
68 70 |
| 4 | Platelets Fibroblasts Muscle |
Leading edge and filopodia Filopodia Nonreactive |
19 20 |
110 110 |
| 5 | Platelets Fibroblasts Muscle |
Leading edge Diffuse Nonreactive |
21 | Many bands |
| 6 | Platelets Fibroblasts Muscle |
Lamellipodia/diffuse Nonreactive Z-band/diffuse |
26 28 |
75 75 |
| 7 | Platelets Fibroblasts Muscle |
Filopodia Nonreactive Diffuse | 30 | 72 |
| 8 | Platelets Fibroblasts Muscle |
Lamellipodium Lamellipodium A-band (myosin-like) |
32 | 43 |
| 9 | Platelets Fibroblasts Muscle |
Leading edge Diffuse Actin-like (I-band) |
33 | 130 |