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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Nanomedicine (Lond). 2012 Apr;7(4):597–615. doi: 10.2217/nnm.12.22

Figure 7. Targeted tumor ablation therapy.

Figure 7

(A) Preparation of single-walled carbon nanotubes conjugated with CD133 mAb antibody (CDSWNTs). (B) UV spectrum of CDSWNTs showing a near infrared maximum at 815 nm. (C) Tumor growth rate and volumes of tumor-bearing nude mice for four different groups: (I) glioblastoma multiforme (GBM)-CD133− cells; (II) GBM-CD133+ cells; (III) GBM-CD133+ cells pretreated with CDSWNTs only; and (IV) GBM-CD133+ cells pretreated with CDSWNTs combined with near infrared laser irradiation. Data shown were the mean ± standard deviation of three experiments (p < 0.001).

EDC: Ethyl(dimethylaminopropyl) carbodiimide; NHS: N-Hydroxysuccinimide; SWNT: Single-walled carbon nanotube.

Reproduced with permission from [63].