Table 3. Summary of k-values for binding to HIV-1 epitopes.
mAb 2F5scFc | Ab3 fraction | |||
UG37 | GGGELDKWASL | UG37 | GGGELDKWASL | |
kon [1/Ms] | 1.9×1005 (1.3) | 1.2×1005 (0.4) | 8.4×1004 (3.4) | 1.9×1005 (0.5) |
koff [1/s] | 9.5×10−04 (3.2) | 3.2×10−04 (1.1) | 2.3×10−03 (1.3) | 6.6×10−04 (3.5) |
KD [nM] | 7.1 (4.3) | 2.7 (0.3) | 33.3 (28.3) | 3.6 (2.4) |
standard deviation in brackets.