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(A) Exploration of the central zone was measured as an index of anxiety-like behavior. LIP- and KA-treated rats from both strains showed increased exploration of the central zone. (B) Total distance traveled. The results are presented as the mean ± SEM. * P<0.05, ** P<0.01, and *** P<0.0001 vs. their respective control groups. Abbreviations: W: Wistar; SD: Sprague-Dawley; LIP: lithium-pilocarpine; KA: kainic acid.
