In this patient with a 0.8 cm tubular carcinoma, low-dose MBI was performed with 296 MBq injection Tc-99 m sestamibi and acquired in eight dynamic frames. Images representing acquisition durations of 2.5, 5, 7.5, and 10 min/breast view were simulated by summing counts from either two, four, six, or eight frames, respectively. Images were acquired with optimized collimation and wide energy window. The average final assessment and individual assessments from four readers are provided, where an assessment of 3 or higher is considered positive.