Table 3.
Compound | R2 | aMax Inh | EC50 (μM) |
---|---|---|---|
1 | 0.82 | 2.3 | |
11a | 0.80 | 3.9 | |
11b | 0.85 | bNT | |
11c | 0.75 | 3.0 | |
11d | 0.79 | 2.5 | |
11e | 0.70 | 8.8 | |
11f | 0.45 | 5.5 | |
11g | 0.50 | 4.0 | |
11h | 1.0 | NT | |
11i | 0.40 | 7.8 | |
11j | 0.30 | 7.4 | |
11k | 0.33 | 1.8 | |
11l | 0.40 | 2.6 | |
11m | 0.50 | 2.5 |
results are average of 2 or more experiments.
Value = fold change relative to DMSO control at 10 μM compound;
NT = not tested. .
All standard deviations ≤ 25%.