Figure 3. The overall anterograde bias of synapsin and α-synuclein population.
(A, B) Cumulative intensity center plots (mean ±SEM) of synapsin and synuclein (N=14 and 21 axons analyzed respectively, from 3–5 separate experiments) are shown. Smoothened fits through the data-points is also shown. The higher diffusiveness of α-synucleinin axons may be responsible for the greater variability in the α-synuclein datasets., compared to synapsin and reflects a limitation of the photoactivation assay (also see Roy et al., 2011).
(C) Overlay of the fits above highlights similarities in the overall anterograde transport of synapsin and α-synuclein.