Table 3.

COMD attempters (n=105) versus non-attempters (n=96): Genotype distributions for HOMER1 and NPTX2 polymorphisms

Locus	SNP	Phenotype	Genotype			Chisq	Genotype p	d.f.	Allele p
HOMER1	rs7713917		AA	AG	GG
		SA+	21	49	35	0.15	0.93	2	0.70
		SA−	21	44	30
	rs4704560		CC	CT	TT
		SA+	27	50	28	0.76	0.68	2	0.67
		SA−	25	40	30
	rs2290639		TT	TA	AA
		SA+	30	39	36	12.42	0.003*	2	0.64
		SA−	14	58	24
	rs2404150		GG	GA	AA
		SA+	26	40	39	6.27	0.04	2	0.11
		SA−	11	47	38
	rs7702760		CC	CA	AA
		SA+	10	44	51	2.84	0.24	2	0.11
		SA−	7	31	58
	rs4132033		GG	GC	CC
		SA+	25	51	29	3.31	0.19	2	0.07
		SA−	33	44	19
	rs10942889		TT	TG	GG
		SA+	27	44	34	2.79	0.25	2	0.13
		SA−	29	46	21
NPTX2	rs1681248		GG	GC	CC
		SA+	93	10	2	FET	0.006*	-	0.02
		SA−	71	24	1
	rs705318		TT	TG	GG
		SA+	14	40	51	5.84	0.05	2	0.05
		SA−	20	40	36
	rs705315		GG	GA	AA
		SA+	93	9	3	FET	0.01*	-	0.07
		SA−	73	22	1

FET: Fisher’s Exact Test

COMD: Childhood-Onset Mood Disorder

SA+: COMD with history of lifetime suicide attempt, n = 119

SA−: COMD with no history of lifetime suicide attempt, n = 109

^*Significant after spectral decomposition (SNPSpD; Nyholt, 2004)