Figure 2.

Development of clinical PVR in Rag-1 KO and WT mice after dispase injection. A total of 10 mice in each group were injected intraocularly with 0.2 U/μl dispase. At the time points specified, the eyes were examined for: (a) macroscopic presentation of PVR symptoms; and (b) histological evidence for PVR as established on H&E-stained sections. (c) Skot ERGs recording α- and β-wave amplitudes. The contralateral untreated eyes were used as controls. The data in both panels represent the cumulative results obtained on 25 Rag-1 KO mice after dispase injection.