Table 1. Characteristics of study subjects.
| Healthy volunteers | Hemodialysis patients | |
|---|---|---|
| n | 12 | 22 |
| Age, yearsa | 38.5 (13.3), 24–61 | 67.7 (12.3), 42–90b |
| Female, n (%) | 8 (67%) | 11 (50%) |
| Weight, kga | NA | 78.2 (16.5), 53.5–113.0 |
| Dialysis adequacy (Kt/V)a | NA | 1.42 (0.31) |
| Daily energy intake (kcal/kg)a | NA | 21.4 (7.9), 10.0–38.0 |
| Daily protein intake (g/kg)a | NA | 0.80, 0.30–1.30 |
| Daily phosphate intake (mg)a | NA | 982 (259), 524–1482 |
| Daily calcium intake (mg)a | NA | 723 (201), 337–1186 |
| Cause of renal failure, n | NA | Small kidneys/unknown etiology (7), glomerulonephritis (4), membranous nephropathy (3), pyelonephritis (2), diabetes mellitus (2), renal vascular disease (2), IgA nephropathy (1), Wegener's granulomatosis (1) |
| Bone ALP concentration (μg/l)a | 13.3, 4.8–26.8 | 15.2, 7.8–85.0 |
| Total ALP activity (U/l)a | 56, 32–105 | 79, 43–275b |
| PTH concentration (ng/l)a | 43, 22–101 | 168, 18–978b |
Abbreviations: ALP, alkaline phosphatase; IgA, immunoglobulin A; NA, not applicable; PTH, parathyroid hormone.
a
Data obtained at the beginning of study.
b
Significantly (P<0.05) different from the value in the healthy controls.
Values for continuous variables are expressed as mean (s.d.), range (where given), or median, range. Further details may be found in Gardham et al.7